Proheart dosing

Both ProHeart 6 and ProHeart 12 are hailed for their efficacy and safety, with the primary difference lying in the duration of protection and the age at which they can be administered. While ProHeart 6 offers a great starting point for younger dogs, ProHeart 12 steps in as a convenient, longer-lasting alternative for dogs over 1 year of age.

Proheart dosing. Vetmedin Dosing Chart. VETMEDIN® (pimobendan) Chewable Tablets: Indications: Management of symptoms of mild, moderate, or severe congestive heart failure (CHF) in dogs caused by MMVD or DCM. Dosage & Administration: Total daily dose: 0.23mg/lb (0.5 mg/kg) body weight. The total dose should be divided into two portions …

Dose. ProHeart 12 Dosing Chart. Heartworm disease is a serious and potentially fatal condition in dogs, caused by parasitic worms living in the heart and …

Mar 23, 2022 · ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ... Sep 20, 2019 · ProHeart 12 can be used in healthy dogs that are one year or older. Because puppies grow rapidly, they tend to need different dosages of heartworm preventative each month, based upon their weight. Many vets recommend using oral or topical heartworm meds through year one, then deciding whether to make the switch. ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.Preventive efficacy of six monthly oral doses of Simparica Trio ®, Heartgard ® Plus, and Interceptor ® Plus against a macrocyclic lactone-resistant strain (ZoeLA) of …ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,

Certification is required prior to the purchase and administration of ProHeart® 6 (moxidectin) and ProHeart® 12 (moxidectin) in your clinic. Certification involves a one-time commitment to watch a video providing product education. Veterinary technicians are encouraged to certify so that they can also administer ProHeart 6 and ProHeart 12. ProHeart 12 Prescribing Information. ProHeart® 6 (moxidectin) delivers 6 months of heartworm disease prevention for dogs with 1 shot. Learn more here. 0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation. ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months, Proheart 12 · Revolution Plus · Rimadyl ... Home / Products / Beef / Overview / Dosing & Administration ... Dosing & Administration. It doesn't take much&...A single dose of ProHeart® 12 was 100% effective in preventing heartworm disease in dogs for a full year in both laboratory and field studies. The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in dogs for 12 months was …ONE BITE can give a dog heartworm disease, ONE ProHeart 12 injection ensures ONE FULL YEAR of constant protection. ProHeart 12 is the only once-yearly injection to prevent heartworm disease in dogs. A convenient once-a-year injection- so you don’t have to worry about forgetting a monthly dose and leaving your best friend exposed to heartworm …

Cardio Pro is a comprehensive formula featuring 12 active ingredients that support cardiovascular health and function in dogs and cats.Background The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods Study 1: safety margin was evaluated as 3 treatments of PH 12 (0× (control); 1× ... ProHeart® FAQ. Lakeside Animal Clinic is happy to offer ProHeart ® 6 and ProHeart® 12, an injectable heartworm prevention administered every six or twelve months. It is a safe, effective, convenient, and economical way to prevent heartworms. If you've ever forgotten to give your dog his or her monthly heartworm prevention, then ProHeart® 6 ... ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for 6 months; however, against a ML-resistant strain, ProHeart 6 was ineffective at the end of 6 months .At THS, we have the resources to treat heartworm in shelter dogs using the AHS-recommended 3-dose melarsomine protocol, which is considered the safest and most effective treatment in most cases. However, at the outreach clinics, where prevalence typically reaches double digits, this is rarely an option.Sep 20, 2019 · ProHeart 12 can be used in healthy dogs that are one year or older. Because puppies grow rapidly, they tend to need different dosages of heartworm preventative each month, based upon their weight. Many vets recommend using oral or topical heartworm meds through year one, then deciding whether to make the switch.

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Jun 9, 2020 ... If you insist on making the comparison, the fluralaner (B) dose is 10x the afoxolaner (NS) dose, or ~3x if you consider 3 monthly doses vs 1 ...ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,If so, then we recommend having your dog tested for heartworm and treated with PROHEART which gives them 12months protection and saves you having to worry about missing their monthly dose. During the months of …ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,Mar 23, 2022 · ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ...

Background The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies using Beagle dogs and one study using ivermectin-sensitive Collies. The recommended dose is 0.5 mg/kg subcutaneously once yearly. Methods Study 1: safety …Hey there, pet lovers! Today, we're diving deep into the world of canine heartworm prevention, specifically focusing on ProHeart 12. You've got questions, and boy, do we have answers! Let's unravel the mystery behind ProHeart 12's side effects and their duration. What's the Buzz About ProHeart 12? 🚀 First off, ProHeart 12 is a revolutionaryIt’s available in four dosing sizes (2-8 lbs., 8.1-25 lbs., 25.1-50 lbs., and 50.1-100 lbs.). Dogs over 100 pounds can still take this medication but will require a combination of chewables for appropriate dosing. Dogs must be at least 2 pounds in size and 6 weeks or older to take this prevention. Simparica TrioProHeart 12 works by releasing small doses of moxidectin into your dog’s bloodstream. This has been tested for years and is proven safe and worthwhile! There are a few side effects that some studies have published. The side effects of ProHeart 12 include vomiting, dizziness, dehydration, and exhaustion. There are no serious effects that would ...heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent andIn 55 dogs with severe heartworm disease (HWD) and treated in this 3-dose manner, 96% had a good or very good outcome with >98% negative for antigenemia 90 days post-therapy. 19 Although symptomatic and even fatal PTE can result from treatment with melarsomine, no case of severe PTE was seen in the 382 dogs of this series. 20 Of the 55 severely ...Proheart 12: dosing chart for dogs (weight in pounds)Proheart dosing chart Proheart 12 dose chartInjection proheart 12 dosing chart. Proheart – a prevenção anual contra o verme do coração canino – viraInjection proheart 12 dosing chart Proheart dosing chartProheart dosing chart.In a well-controlled 605-day US field study, two doses of ProHeart 12 were administered subcutaneously at a dosage of 0.5 mg/kg (0.23 mg/lb), 12 months apart. A total of 235, 226 and 222 ProHeart 12-treated dogs completed the heartworm testing (adult heartworm antigen and microfilariae) on Days 365, 480 and 605, respectively.

ProHeart 12-related findings included edema and thickening of the injection site. Ivermectin-Sensitive Collie Safety: In a laboratory study, 15 ivermectin-sensitive Collie dogs in three treatment groups were administered one dose of saline and one dose of ProHeart 12, 21 days apart. Each dog served as its own control and the order of ...

Bone broth is a nutritious and delicious way to get your daily dose of minerals, vitamins, and collagen. It’s also incredibly easy to make at home, so you can enjoy it any time you...ProHeart 6 and ProHeart 12 See Prescribing Information for ProHeart 6 and ProHeart 12. Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug.ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. III. Dosage Form, Route of Administration and Dosage: Dosage Form: ProHeart 6 (moxidectin) is provided in two separate vials that require mixing prior to use.ProHeart 6 administered at 3 times the recommended dose in dogs with patent heartworm infections and up to 5 times the recommended dose in ivermectin-sensitive collies did not cause any adverse reactions. ProHeart 6 administered at 3 times the recommended dose did not adversely affect the reproductive performance of male or female dogs.ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a varietyA once yearly proheart injection, is very affordable and is the absolute gold standard in heartworm prevention worldwide. Why monthly dosing is a risky option. Recent survey studies conducted in the United States have revealed that of those patients not receiving the annual Proheart heartworm injection, only 75% are on a monthly preventative.Dose. ProHeart 12 Dosing Chart. Heartworm disease is a serious and potentially fatal condition in dogs, caused by parasitic worms living in the heart and …May 29, 2012 ... My Vet dose not use the ProHeart 6 . He told me it killed dogs . He ... dosing. I'm not sure WHAT I'll be giving my dogs if Novartis doesn't ...heartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistent effectiveness has not been established for this indication. Re-infection with A. caninum andThe animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient.

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This long-lasting activity enables owners to reliably protect their dogs with twice-yearly dosing requirements. ProHeart® 12 (PH 12) (Zoetis, Parsippany, NJ, USA) uses the same microsphere technology as PH 6 but with a higher final concentration of microspheres, providing 3× (0.5 mg/kg moxidectin) the dose rate of PH 6.PROHEART is the original brand containing moxidectin tablets for heartworm prevention in dogs. Moxidectin is a systemic macrocyclic lactone introduced in the 1990s (by AMERICA CYANAMID → FORT DODGE → PFIZER → ZOETIS) effective against mites, heartworms and roundworms. It has no effect on fleas.ProHeart 6 is an injectable medication that is used in dogs 6 months of age or older to prevent heartworm disease. Your veterinarian will administer ProHeart 6 as a single injection under your dog’s skin. Once the drug is given, it continuously prevents heartworm disease for 6 months. Using ProHeart 6 means that you don’t need to …Client Information Sheet. Review this information with your veterinarian each time your dog receives ProHeart 6. When your veterinarian prescribes medicine for your dog, it’s sometimes hard to remember all the information discussed during the visit. This sheet is provided as a summary, but if. you have any additional questions you should ...Does your "3 mg" gummy actually contain 10 milligrams of melatonin? According to a recent study, it might. If you’ve ever felt like your melatonin gummies hit harder than you expec...Nov 15, 2019 ... ProHeart – a New Alternative to Heartworm Prevention ... – they can customize the dose ... Update – If we dispense Sileo to you, it is imperative ...A single dose of 7.5 mg/kg (3X the recommended dose) can result in pulmonary inflammation, edema, and death. Daily administration of these doses for 14 days caused renal damage in healthy dogs. Adverse reactions, primarily at the injection sites, were seen at the recommended dose in clinical trials (see ADVERSE REACTIONS).Extended Protection: ProHeart 6 provides six months of continuous heartworm disease prevention, while ProHeart 12 offers a full year of coverage. Convenience: A single injection eliminates the need for monthly reminders. Veterinarian-Administered: Ensures proper dosage and offers an opportunity for a health check-up.The determination of the correct ProHeart dosage is a meticulous process that veterinarians undertake with the utmost care, ensuring the safety and efficacy of the treatment. The dosage is primarily based on the dog's weight, with ProHeart being available in different strengths to cater to a wide range of sizes.This site is intended for U.S. Animal Healthcare Professionals. The product information provided in this site is intended only for residents of the United States. The products discussed herein may not have marketing authorization or … An injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that were inoculated with infective larvae 365 days after receiving a dose of 0.5 mg/kg. 2,3 ….

Hey there, pet lovers! Today, we're diving deep into the world of canine heartworm prevention, specifically focusing on ProHeart 12. You've got questions, and boy, do we have answers! Let's unravel the mystery behind ProHeart 12's side effects and their duration. What's the Buzz About ProHeart 12? 🚀 First off, ProHeart 12 is a revolutionaryheartworm preventive product, ProHeart 6 should be given within one month of the last dose of the former medication. ProHeart 6 eliminates the larval and adult stages of A. caninum and U. stenocephala present at the time of treatment. However, persistentandAn injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that were inoculated with infective larvae 365 days after receiving a dose of 0.5 mg/kg. 2,3 The constituted suspension is for subcutaneous injection at the rate of 0.05 mL/kg body weight to provide 0.17 mg moxidectin/kg. ProHeart 6 can be administered to dogs 6 months of age and older. For growing dogs, dose to the average weight during the 6 month effective period. Administration may be repeated at 6 months intervals. ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for …ProHeart® 12 is an injectable heartworm disease preventative that provides 12 months of continuous protection against heartworm disease with a single veterinary-administered dose. See products. 10 ml, 1/Pkg (With 1 Client Information Pad)ProHeart 6 is a medication that prevents heartworm disease in dogs 6 months of age and older. Your veterinarian . gives it to your dog via an injection and it protects your dog …The constituted suspension is for subcutaneous injection at the rate of 0.05 mL/kg body weight to provide 0.17 mg moxidectin/kg. ProHeart 6 can be administered to dogs 6 months of age and older. For growing dogs, dose to the average weight during the 6 month effective period. Administration may be repeated at 6 months intervals.Heartworm disease. Heartworms are parasites that are able to live inside the arteries of the lung and chambers of a pet’s heart and feed on surrounding blood. In severe cases heartworms can grow up to 30cm long and 2cm thick in populations of over 200. The offspring of a heartworm are more commonly referred to as Microfilariae, which can be ...ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ... Proheart dosing, ProHeart 6 is a heartworm preventive and hookworm treatment for dogs six months and older. Learn how to mix, measure and administer the subcutaneous injection, and follow …, Heartworm Treatment Dosage Calculator. The AHS Treatment Plan app can help you create customized canine heartworm treatment regimens using your tablet, smartphone, or other electronic device. Select drugs, calculate dosages, and customize therapy for individual pets with heartworm disease. The uncomplicated app design makes it easy to use right ..., ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes., In a well-controlled 605-day US field study, two doses of ProHeart 12 were administered subcutaneously at a dosage of 0.5 mg/kg (0.23 mg/lb), 12 months apart. A total of 235, 226 and 222 ProHeart 12-treated dogs completed the heartworm testing (adult None ..., 12 chances to miss a dose! When life gets busy, it can be tough to stay on top of monthly dosing— • and many pet owners do forget.2 Dogs may vomit or spit out the chews, which means you may have to redose. Some dogs refuse to eat "treat-like Is ProHeart, 0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation., Injectable heartworm preventatives (containing moxidectin) offer an alternative to oral and topical treatments. ProHeart 6, for example, can be used in puppies as young as six months of age, while ProHeart 12 is suitable for dogs over one year. These injections protect for six or 12 months, depending on the chosen product., ProHeart 12 Dosing Chart ProHeart 12 vs. Heartgard for Dogs 🐾 Category: Toxicity Published on: March 28, 2024 March 28, 2024 Author: Bestie Paws Like: 26 Comment: 0 Leave a Reply Cancel reply Your email …, Zoetis , ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months, , See full list on vetlabel.com , ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ..., Sep 29, 2023 · Proheart is an INJECTABLE heartworm prevention that is only given every 6 months! …” Racine Veterinary Hospital writes: “Proheart 6 is an injectable heartworm prevention. 1 injection lasts 6 months, which means you don’t have to worry about missing a dose…” Eastpoint Vet writes: “Proheart injections are going well this month … , Dose: The recommended subcutaneous dose is 0.05 mL of the constituted suspension/kg body weight (0.0227 mL/lb.). This amount of suspension will provide 0.17 mg …, Learn how to get certified for ProHeart, a convenient and effective heartworm prevention for dogs, by watching a video from Zoetis., In a well-controlled 605-day US field study, two doses of ProHeart 12 were administered subcutaneously at a dosage of 0.5 mg/kg (0.23 mg/lb), 12 months apart. A total of 235, 226 and 222 ProHeart 12-treated dogs completed the heartworm testing (adult heartworm antigen and microfilariae) on Days 365, 480 and 605, respectively., An injectable moxidectin microsphere formulation (ProHeart 12; Zoetis, zoetisus.com) was shown to be 100% effective in the prevention of development of D immitis in dogs that were inoculated with infective larvae 365 days after receiving a dose of 0.5 mg/kg. 2,3, Feb 27, 2024 · ProHeart 6 is indicated for use in dogs six months of age and older for the prevention of heartworm disease caused by Dirofilaria immitis for 6 months. ProHeart 6 is indicated for the treatment of existing larval and adult hookworm (Ancylostoma caninum and Uncinaria stenocephala) infections. ProHeart 6 (moxidectin) Dosage And Administration , To properly protect your dog, ProHeart 6 should be administered within 1 month before mosquitoes appear where you live. If you are switching from another heartworm preventive medication, ProHeart 6 should be administered within 1 month after the last dose of, ProHeart Injection is a veterinarian-administered injectable solution that provides long-term protection against heartworm disease in dogs. Depending on the version (ProHeart 6 or ProHeart 12), it can offer 6 or 12 months of …, People should avoid inhalation, contact with eyes, or accidental self-injection. Certification is required before veterinarians and staff administer these products. See Prescribing Information for ProHeart 6 and ProHeart 12. To keep your dog protected from heartworm disease, it’s important to make sure there are no gaps in their protection., 0.50 mg ProHeart 6/kg bodyweight (high-dose) Route of Administration: Subcutaneous injection in the dorsum of the neck. Test Duration: 327 days (treatment to necropsy). Study Design: All dogs were determined to be negative for D. immitis by antigen test and modified Knott’s test prior to study initiation., ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti …, ProHeart 6, an extended-release injectable suspension using the exact same formulation as ProHeart 12 but at one-third the dose (0.17 mg/kg) of ProHeart 12, was 99.5% effective against the same JYD-34 strain, when treatment was administered 2 …, ProHeart 12 prevents the development of heartworm disease caused by D. immitis for 12 months. For dogs not previously on heartworm preventive or having lapsed beyond 12 months of a prior ProHeart 12 dose, the product should be given within 1 month of exposure to mosquitoes. Follow-up treatments may be given every 12 months,, ProHeart 12 is indicated for use in dogs 12 months of age and older for the accurate dosing calculate each dose based on the dog's weight at the time ... proheart pi ProHeart® 6(moxidectin) ProHeart 6 is indicated for use in dogs six months of age and older for the calculate each dose based on the dog's weight at the time of treatment. proheartcis pi, ProHeart 6 administered up to 5 times the recommended dose in 7-8 month old puppies did not cause any systemic adverse effects. In well controlled clinical field studies, ProHeart 6 was used in conjunction with a variety of veterinary products including anthelmintics, antiparasitics, antibiotics, analgesics, steroids, non-steroidal anti ..., The animal health information contained herein is provided for educational purposes only and is not intended to replace discussions with an animal healthcare professional. All decisions regarding the care of a veterinary patient must be made with an animal healthcare professional, considering the unique characteristics of the patient. , Sep 29, 2023 · Proheart is an INJECTABLE heartworm prevention that is only given every 6 months! …” Racine Veterinary Hospital writes: “Proheart 6 is an injectable heartworm prevention. 1 injection lasts 6 months, which means you don’t have to worry about missing a dose…” Eastpoint Vet writes: “Proheart injections are going well this month … , with ProHeart 6 either 1, 3, or 5 times at the recommended dose of 0.17 mg/kg did not demonstrate any clinical signs, laboratory findings, or necropsy lesions associated with systemic or target organ toxicity.2In addition, when ProHeart 6 was administered to, ProHeart offers convenience with less frequent dosing, while Simparica Trio appeals to those who prefer oral administration. Round 3: Safety and Side Effects Both medications have demonstrated safety in numerous studies, but as with all treatments, side effects can occur., dose based on the dog’s weight at the time of treatment. Do not overdose growing puppies in anticipation of their expected adult weight. The following dosage chart may be used as a guide. Some dogs treated with ProHeart 6 in laboratory effectiveness studies developed transient, localized inflammatory injection DOSAGE CHART site reactions. , Apr 26, 2021 · ProHeart ® 6, the same microsphere formulation as ProHeart 12 but administered at one-third the dose (0.17 mg/kg) of ProHeart 12, was 100% effective in preventing the development of a susceptible heartworm strain for 6 months; however, against a ML-resistant strain, ProHeart 6 was ineffective at the end of 6 months .